Gene description for PTPA
Gene name protein phosphatase 2 phosphatase activator
Gene symbol PTPA
Other names/aliases PARK25
PP2A
PPP2R4
PR53
Species Homo sapiens
 Experiment description of studies that identified PTPA in Pancreatic cancer cells

1
Experiment ID2678
Identified moleculeProtein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Mass spectrometry
PubMed ID 35656858   
OrganismHomo sapiens
Experiment descriptionA multi-omics approach identifies pancreatic cancer cell extracellular vesicles as mediators of the unfolded protein response in normal pancreatic epithelial cells
AuthorsHinzman CP, Singh B, Bansal S, Li Y, Iliuk A, Girgis M, Herremans KM, Trevino JG, Singh VK, Banerjee PP, Cheema AK.
Journal name J Extracell Vesicles
Publication year2022
SamplePancreatic cancer cells
Sample namePANC-1
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Lipid
Metabolite
Methods used in the studyWestern blotting
Mass spectrometry
EV-TRACK -

2
Experiment ID2679
Identified moleculeProtein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Mass spectrometry
PubMed ID 35656858   
OrganismHomo sapiens
Experiment descriptionA multi-omics approach identifies pancreatic cancer cell extracellular vesicles as mediators of the unfolded protein response in normal pancreatic epithelial cells
AuthorsHinzman CP, Singh B, Bansal S, Li Y, Iliuk A, Girgis M, Herremans KM, Trevino JG, Singh VK, Banerjee PP, Cheema AK.
Journal name J Extracell Vesicles
Publication year2022
SamplePancreatic cancer cells
Sample nameMiaPaCa-2
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Lipid
Metabolite
Methods used in the studyWestern blotting
Mass spectrometry
EV-TRACK -

3
Experiment ID2680
Identified moleculeProtein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Mass spectrometry
PubMed ID 35656858   
OrganismHomo sapiens
Experiment descriptionA multi-omics approach identifies pancreatic cancer cell extracellular vesicles as mediators of the unfolded protein response in normal pancreatic epithelial cells
AuthorsHinzman CP, Singh B, Bansal S, Li Y, Iliuk A, Girgis M, Herremans KM, Trevino JG, Singh VK, Banerjee PP, Cheema AK.
Journal name J Extracell Vesicles
Publication year2022
SamplePancreatic cancer cells
Sample nameCapan-1
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Lipid
Metabolite
Methods used in the studyWestern blotting
Mass spectrometry
EV-TRACK -

4
Experiment ID2681
Identified moleculeProtein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Mass spectrometry
PubMed ID 35656858   
OrganismHomo sapiens
Experiment descriptionA multi-omics approach identifies pancreatic cancer cell extracellular vesicles as mediators of the unfolded protein response in normal pancreatic epithelial cells
AuthorsHinzman CP, Singh B, Bansal S, Li Y, Iliuk A, Girgis M, Herremans KM, Trevino JG, Singh VK, Banerjee PP, Cheema AK.
Journal name J Extracell Vesicles
Publication year2022
SamplePancreatic cancer cells
Sample nameSW-1990
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Lipid
Metabolite
Methods used in the studyWestern blotting
Mass spectrometry
EV-TRACK -

5
Experiment ID2682
Identified moleculeProtein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Mass spectrometry
PubMed ID 35656858   
OrganismHomo sapiens
Experiment descriptionA multi-omics approach identifies pancreatic cancer cell extracellular vesicles as mediators of the unfolded protein response in normal pancreatic epithelial cells
AuthorsHinzman CP, Singh B, Bansal S, Li Y, Iliuk A, Girgis M, Herremans KM, Trevino JG, Singh VK, Banerjee PP, Cheema AK.
Journal name J Extracell Vesicles
Publication year2022
SamplePancreatic cancer cells
Sample namePPCL-68 (PDX)
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Lipid
Metabolite
Methods used in the studyWestern blotting
Mass spectrometry
EV-TRACK -

6
Experiment ID2683
Identified moleculeProtein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Mass spectrometry
PubMed ID 35656858   
OrganismHomo sapiens
Experiment descriptionA multi-omics approach identifies pancreatic cancer cell extracellular vesicles as mediators of the unfolded protein response in normal pancreatic epithelial cells
AuthorsHinzman CP, Singh B, Bansal S, Li Y, Iliuk A, Girgis M, Herremans KM, Trevino JG, Singh VK, Banerjee PP, Cheema AK.
Journal name J Extracell Vesicles
Publication year2022
SamplePancreatic cancer cells
Sample namePPCL-46 (PDX)
Isolation/purification methodsDifferential centrifugation
Filtration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Lipid
Metabolite
Methods used in the studyWestern blotting
Mass spectrometry
EV-TRACK -

7
Experiment ID2686
Identified moleculeProtein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Mass spectrometry
PubMed ID 35656858   
OrganismHomo sapiens
Experiment descriptionA multi-omics approach identifies pancreatic cancer cell extracellular vesicles as mediators of the unfolded protein response in normal pancreatic epithelial cells
AuthorsHinzman CP, Singh B, Bansal S, Li Y, Iliuk A, Girgis M, Herremans KM, Trevino JG, Singh VK, Banerjee PP, Cheema AK.
Journal name J Extracell Vesicles
Publication year2022
SamplePancreatic cancer cells
Sample namePANC-1
Isolation/purification methodsEVtrap
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -

8
Experiment ID2687
Identified moleculeProtein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Mass spectrometry
PubMed ID 35656858   
OrganismHomo sapiens
Experiment descriptionA multi-omics approach identifies pancreatic cancer cell extracellular vesicles as mediators of the unfolded protein response in normal pancreatic epithelial cells
AuthorsHinzman CP, Singh B, Bansal S, Li Y, Iliuk A, Girgis M, Herremans KM, Trevino JG, Singh VK, Banerjee PP, Cheema AK.
Journal name J Extracell Vesicles
Publication year2022
SamplePancreatic cancer cells
Sample nameMiaPaCa-2
Isolation/purification methodsEVtrap
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -

9
Experiment ID2688
Identified moleculeProtein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Mass spectrometry
PubMed ID 35656858   
OrganismHomo sapiens
Experiment descriptionA multi-omics approach identifies pancreatic cancer cell extracellular vesicles as mediators of the unfolded protein response in normal pancreatic epithelial cells
AuthorsHinzman CP, Singh B, Bansal S, Li Y, Iliuk A, Girgis M, Herremans KM, Trevino JG, Singh VK, Banerjee PP, Cheema AK.
Journal name J Extracell Vesicles
Publication year2022
SamplePancreatic cancer cells
Sample nameCapan-1
Isolation/purification methodsEVtrap
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -

10
Experiment ID2689
Identified moleculeProtein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Mass spectrometry
PubMed ID 35656858   
OrganismHomo sapiens
Experiment descriptionA multi-omics approach identifies pancreatic cancer cell extracellular vesicles as mediators of the unfolded protein response in normal pancreatic epithelial cells
AuthorsHinzman CP, Singh B, Bansal S, Li Y, Iliuk A, Girgis M, Herremans KM, Trevino JG, Singh VK, Banerjee PP, Cheema AK.
Journal name J Extracell Vesicles
Publication year2022
SamplePancreatic cancer cells
Sample nameSW-1990
Isolation/purification methodsEVtrap
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -

11
Experiment ID2690
Identified moleculeProtein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Mass spectrometry
PubMed ID 35656858   
OrganismHomo sapiens
Experiment descriptionA multi-omics approach identifies pancreatic cancer cell extracellular vesicles as mediators of the unfolded protein response in normal pancreatic epithelial cells
AuthorsHinzman CP, Singh B, Bansal S, Li Y, Iliuk A, Girgis M, Herremans KM, Trevino JG, Singh VK, Banerjee PP, Cheema AK.
Journal name J Extracell Vesicles
Publication year2022
SamplePancreatic cancer cells
Sample namePPCL-68 (PDX)
Isolation/purification methodsEVtrap
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -

12
Experiment ID2690
Identified moleculeProtein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Mass spectrometry
PubMed ID 35656858   
OrganismHomo sapiens
Experiment descriptionA multi-omics approach identifies pancreatic cancer cell extracellular vesicles as mediators of the unfolded protein response in normal pancreatic epithelial cells
AuthorsHinzman CP, Singh B, Bansal S, Li Y, Iliuk A, Girgis M, Herremans KM, Trevino JG, Singh VK, Banerjee PP, Cheema AK.
Journal name J Extracell Vesicles
Publication year2022
SamplePancreatic cancer cells
Sample namePPCL-68 (PDX)
Isolation/purification methodsEVtrap
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -

13
Experiment ID2691
Identified moleculeProtein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method Mass spectrometry
PubMed ID 35656858   
OrganismHomo sapiens
Experiment descriptionA multi-omics approach identifies pancreatic cancer cell extracellular vesicles as mediators of the unfolded protein response in normal pancreatic epithelial cells
AuthorsHinzman CP, Singh B, Bansal S, Li Y, Iliuk A, Girgis M, Herremans KM, Trevino JG, Singh VK, Banerjee PP, Cheema AK.
Journal name J Extracell Vesicles
Publication year2022
SamplePancreatic cancer cells
Sample namePPCL-46 (PDX)
Isolation/purification methodsEVtrap
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -

14
Experiment ID3346
Identified moleculeprotein
Extracellular vesicle typeSupermeres
MISEVEV-like nanoparticles
Identification method Mass spectrometry
PubMed ID 34887515   
OrganismHomo sapiens
Experiment descriptionSupermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
AuthorsZhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ.
Journal name Nat Cell Biol
Publication year2021
SamplePancreatic cancer cells
Sample namePANC-1
Isolation/purification methodsDifferential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
Mass spectrometry
ELISA
EV-TRACK -

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